Trisodium Hedta: What Is It, Cosmetic Uses, Benefits & Side Effects

Curious about this ingredient? In this article we're explaining exactly what it is and why it's used within cosmetic formulations.
Updated on: June 30, 2025
Share:
Inside this article:

We verify all information on this page using publicly available nomenclature standards from The Personal Care Products Council (PCPC), the European Commission's CosIng database and documentation provided directly by ingredient manufacturers. Our analysis is based on technical data from these sources to ensure accuracy and reliability.

What Is Trisodium Hedta?

Trisodium Hedta is the shortened trade name for trisodium 2-(carboxylatomethyl(2-hydroxyethyl)amino)ethyliminodi(acetate), a salt derived from a larger family of chelating agents often used to bind metal ions. It is synthesized by reacting ethylenediamine, chloroacetic acid and sodium hydroxide, then adding a controlled amount of hydroxyethyl groups to fine-tune its solubility and metal-binding strength. The result is a white to off-white powder or clear aqueous solution that dissolves readily in water.

The cosmetic industry adopted Trisodium Hedta in the late 20th century as formulators sought safer and more versatile alternatives to older chelators such as EDTA. By locking up trace metals that may enter a product through water, pigments or plant extracts, the ingredient helps stabilize formulas without the need for harsher preservatives. Today you will most often see it in facial cleansers, toners, sheet masks, anti-aging serums, moisturizers, hair conditioners and color-protect shampoos where long-term clarity, color and texture are important.

Trisodium Hedta’s Cosmetic Benefits/Uses

As a chelating agent, Trisodium Hedta binds with tiny amounts of iron, copper, calcium and other metal ions that can otherwise cause a product to discolor, separate or lose effectiveness. By capturing these metals it keeps preservatives working longer, maintains a lotion’s smooth feel and helps fragrances and colorants stay true over the full shelf life.

Who Can Use Trisodium Hedta

Because Trisodium Hedta works exclusively as a metal binder and does not act on the skin itself, it is considered suitable for every skin type including oily, dry, combination, sensitive and breakout-prone skin. It has no known occlusive or irritating properties so it rarely triggers flare-ups in conditions such as rosacea or eczema.

The ingredient is synthesized from simple mineral and petrochemical feedstocks and contains no animal-derived components, which makes it acceptable for both vegans and vegetarians. As always, check the full product label to be sure the overall formula meets your personal ethics.

Topical use during pregnancy or while breastfeeding is generally viewed as low risk because the molecule is too large to penetrate deeply and is present at very small percentages. This is not medical advice; anyone who is pregnant or nursing should consult a physician before adding new products to a routine to be safe.

Trisodium Hedta does not absorb UV light so it does not cause photosensitivity. It also plays nicely with vitamin C, retinoids and exfoliating acids, meaning you do not need to adjust the timing of those actives when using a product that contains this chelator.

Potential Side Effects/Adverse Reactions

Individual responses to any cosmetic ingredient can vary. The following points outline potential side effects that may occur, though they are uncommon when products are formulated correctly and used as directed.

  • Mild skin irritation such as temporary redness or itching in very sensitive individuals
  • Eye irritation if a concentrated solution accidentally gets into the eyes
  • Contact dermatitis in users with a rare specific allergy to chelating agents

If you experience any of these reactions discontinue use immediately and seek guidance from a healthcare professional or dermatologist.

Comedogenic Rating

Rating: 0 / 5

Trisodium Hedta is a small water-soluble salt that sits on the surface of a formula rather than on your pores. It does not form a film or trap oil, so it cannot clog follicles. For these reasons it earns a solid zero on the comedogenic scale. This makes it perfectly fine for people who are prone to acne or frequent breakouts.

The only time pore problems could occur is if the overall product is rich in heavy oils or waxes that overshadow the chelator’s non-comedogenic nature.

Summary

Trisodium Hedta’s main job is to grab stray metal ions so preservatives stay active, colors stay true and textures stay smooth. It performs this task by surrounding metals and keeping them from reacting with other ingredients.

Although it shows up less often than powerhouse chelators like EDTA, formulators who want a gentler or more biodegradable option are turning to it more each year. You will spot it in a growing range of cleansers, serums and hair care lines.

Safety profiles from both industry and independent reviews rate it as low risk at the tiny levels used in cosmetics. Still, everyone’s skin is unique so give any new product a quick patch test first to keep your routine worry-free.

Was this article helpful?
More from Glooshi:
ADVERTISEMENT
Get all our top headlines in beauty.
Delivered right to your inbox each week. Zero spam, all goodness, opt-out at anytime.
This site is protected by reCAPTCHA and the Google Privacy Policy and Terms of Service apply.
Get the latest beauty news, top product recommendations & brand-exclusive discount codes direct to your inbox.
Send good feedback:

All feedback is greatly appreciated, anonymous, and will be used to improve the quality of our articles.

This site is protected by reCAPTCHA and the Google Privacy Policy and Terms of Service apply.
Send bad feedback:

All feedback is greatly appreciated, anonymous, and will be used to improve the quality of our articles.

This site is protected by reCAPTCHA and the Google Privacy Policy and Terms of Service apply.
Search