Dipentaerythrityl Pentahydroxystearate/Pentaisostearate: What Is It, Cosmetic Uses, Benefits & Side Effects

Curious about this ingredient? In this article we're explaining exactly what it is and why it's used within cosmetic formulations.
Updated on: June 27, 2025
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We verify all information on this page using publicly available nomenclature standards from The Personal Care Products Council (PCPC), the European Commission's CosIng database and documentation provided directly by ingredient manufacturers. Our analysis is based on technical data from these sources to ensure accuracy and reliability.

What Is Dipentaerythrityl Pentahydroxystearate/Pentaisostearate?

Dipentaerythrityl Pentahydroxystearate and Dipentaerythrityl Pentaisostearate are fatty acid esters made by reacting dipentaerythritol, a sugar-like alcohol, with hydroxystearic or isostearic acid that usually comes from plant oils such as castor or soybean. Chemists first explored this family of esters in the late 20th century while looking for ways to make creams feel richer without relying on heavy waxes. The ingredient is produced through a straightforward esterification process: the alcohol and fatty acids are heated together with a catalyst until they bond, then the mixture is purified and cooled into a soft waxy solid. Because it is stable, non-greasy and easy to blend, formulators add it to many personal care items, including moisturizers, night creams, sunscreens, foundations, lipsticks, balms and rinse-off masks.

Dipentaerythrityl Pentahydroxystearate/Pentaisostearate’s Cosmetic Benefits/Uses

This ingredient pulls its weight in a formula by improving both how a product feels and how it looks on the skin.

  • Skin conditioning: The fatty nature of the ester leaves a light, velvety film that softens rough patches and helps the skin hold on to water, giving a smoother appearance
  • Viscosity controlling: It thickens the oil phase just enough to stop a lotion from running while avoiding the heavy feel that some waxes bring, which creates a creamy texture that spreads easily and stays put

Who Can Use Dipentaerythrityl Pentahydroxystearate/Pentaisostearate?

Thanks to its lightweight cushy finish this ester works for nearly every skin type. Dry and mature skin appreciate the soft film it leaves behind while normal, combo and even oily skin usually find it less greasy than traditional waxes so it rarely feels heavy or clogs pores. Extremely acne-prone users who break out from most oils might still prefer to patch in a small area first, but for the majority it is considered low risk.

The raw material is typically sourced from plant oils and contains no animal by-products which makes it suitable for vegans and vegetarians. Always double-check the full ingredient list of the finished product because brands sometimes pair it with beeswax or other animal derived additives.

No specific warnings exist for pregnancy or breastfeeding. The ester is not absorbed in meaningful amounts and has a solid safety record, yet this is not medical advice and anyone who is pregnant or nursing should run new skincare products past a qualified doctor to be on the safe side.

Dipentaerythrityl Pentahydroxystearate/Pentaisostearate does not increase photosensitivity, so there is no extra sun-related caution beyond the usual daily sunscreen recommendation. It also plays well with common actives such as retinoids, vitamin C and exfoliating acids without destabilising them.

Potential Side Effects/Adverse Reactions

Side effects and reactions to the topical use of Dipentaerythrityl Pentahydroxystearate/Pentaisostearate can vary from person to person. The points below list potential issues yet they are uncommon when the ingredient is used at normal cosmetic levels.

  • Mild skin irritation such as redness or itching in very sensitive individuals
  • Allergic contact dermatitis if the user has a rare specific allergy to the ester or trace impurities
  • Temporary clogged pores or small breakouts in users who react to most fatty ingredients
  • Stinging or watering if the product accidentally gets into the eyes

If any of these effects occur stop using the product and seek advice from a healthcare professional if symptoms persist.

Comedogenic Rating

Rating: 1/5

This ester sits low on the comedogenic scale because its branched fatty acid chains create a light breathable film that is less likely to clog pores than straight-chain oils or heavier waxes. It melts quickly on contact with skin and does not harden inside follicles which further limits congestion. Most acne-prone individuals can use it without issues, although extremely reactive skin might still prefer simpler formulas.

No scientific studies flag it as a major pore-blocker and it is often used in foundations and moisturizers marketed for all skin types which supports its low rating. The final product’s full formula, especially added butters or occlusives, will ultimately determine if the product feels too rich for breakout-prone skin.

Summary

Dipentaerythrityl Pentahydroxystearate and its isostearate cousin act mainly as skin conditioners and viscosity controllers. Their branched fatty chains soften rough texture, slow water loss and give creams a silky cushion while thickening the oil phase just enough to create a stable smooth emulsion.

The ingredient is a quiet workhorse rather than a star act. It is common in professional lab kits yet rarely highlighted on front labels, so consumers may use it daily without noticing. You will spot it in mid-range and prestige skincare as well as color cosmetics where a velvety non-greasy feel is desired.

Toxicology data shows it is non-sensitizing non-phototoxic and virtually non-irritating at the levels used in cosmetics, making it safe for most people. As with any new product though it is smart to patch test first to check how your unique skin responds.

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