Lactococcus/Leuconostoc/Lactobacillus/Zygosaccharomyces/Milk Ferment: What Is It, Cosmetic Uses, Benefits & Side Effects

Curious about this ingredient? In this article we're explaining exactly what it is and why it's used within cosmetic formulations.
Updated on: July 1, 2025
Share:
Inside this article:

We verify all information on this page using publicly available nomenclature standards from The Personal Care Products Council (PCPC), the European Commission's CosIng database and documentation provided directly by ingredient manufacturers. Our analysis is based on technical data from these sources to ensure accuracy and reliability.

What Is Lactococcus/Leuconostoc/Lactobacillus/Zygosaccharomyces/Milk Ferment?

Lactococcus/Leuconostoc/Lactobacillus/Zygosaccharomyces/Milk Ferment is a fermented milk ingredient created when four friendly microbes—Lactococcus, Leuconostoc, Lactobacillus and Zygosaccharomyces—are added to dairy. As they digest the natural sugars and proteins in milk, they break them down into smaller compounds like peptides, amino acids and vitamins that can be kind to skin. Fermented milk has been used for centuries in traditional beauty rituals, but modern labs refined the process in the 1990s when the rise of probiotics in skincare sparked interest in postbiotic extracts that could help support the skin barrier. To make the ingredient, fresh milk is pasteurized, inoculated with the four microorganisms then allowed to ferment under controlled temperatures. The finished liquid is filtered to remove most of the live microbes, concentrating the skin friendly by-products into a stable cosmetic ingredient. You will most often see it in moisturizers, soothing masks, gentle cleansers, anti-aging serums and barrier repair creams where brands want to add a calming probiotic-inspired touch.

Lactococcus/Leuconostoc/Lactobacillus/Zygosaccharomyces/Milk Ferment’s Cosmetic Benefits/Uses

This fermented blend is classed as a skin protecting agent. By delivering lightweight peptides and vitamins, it can help reinforce the skin’s natural barrier so skin retains moisture better and feels less reactive. Formulators reach for it when they want to create products that calm redness, soften dryness and leave the complexion feeling balanced.

Who Can Use Lactococcus/Leuconostoc/Lactobacillus/Zygosaccharomyces/Milk Ferment

This fermented milk extract is generally well tolerated by all skin types, including dry, normal, combination, oily and sensitive skin, because its main job is to support the skin barrier rather than strip or irritate. Extremely acne-prone users may prefer lighter products that include the ferment so the formula as a whole does not feel heavy, but the ingredient itself is not considered pore clogging.

Because it is derived from cow’s milk the ferment is unsuitable for vegans. It can fit into a vegetarian lifestyle since many vegetarians consume dairy. Anyone with a confirmed milk protein allergy should avoid it even though the fermentation process breaks down casein and lactose, as trace proteins could remain.

Pregnant and breastfeeding women can typically use products containing this ingredient because it acts only on the skin’s surface and is not known to penetrate deeply or enter the bloodstream. This is not medical advice and women who are expecting or nursing should run any skincare product past their doctor just to be safe.

The ferment does not make skin more sensitive to sunlight and can be used both morning and night without increasing the risk of sunburn. As with any new skincare ingredient, paying attention to how your skin feels during the first few uses is wise.

Potential Side Effects/Adverse Reactions

Responses to topical Lactococcus/Leuconostoc/Lactobacillus/Zygosaccharomyces/Milk Ferment differ from person to person. The effects below are possible but not likely for most users when a product is properly formulated and used as directed.

  • Redness or stinging in very sensitive skin
  • Mild itching or tightness if you have an existing dairy allergy
  • Contact dermatitis triggered by other ingredients in the same formula rather than the ferment itself

If you notice persistent irritation stop using the product and consult a healthcare professional.

Comedogenic Rating

Rating: 1 out of 5

This fermented milk extract is water based, low in oils and mostly made up of small peptides and sugars that do not tend to block pores. It earns a 1 rather than a flat 0 because trace milk lipids can remain after fermentation, though the amount is usually negligible in a finished formula.

Suitable for acne-prone or breakout-prone skin in most cases. Anyone extremely sensitive to dairy residues may prefer to trial it in a lightweight product first.

Summary

Lactococcus/Leuconostoc/Lactobacillus/Zygosaccharomyces/Milk Ferment works as a skin-protecting ingredient. During fermentation the microbes break down milk proteins and sugars into peptides, amino acids and vitamins that sit on the surface of skin, reinforce the moisture barrier and calm visible redness. Its main appeal is a gentle boost to barrier strength without heaviness.

While not as famous as hyaluronic acid or niacinamide, this ferment is gaining traction in moisturizers and soothing serums aimed at sensitive skin fans who like probiotic-inspired formulas.

Safety profiles show it is generally well tolerated by all skin types except those with confirmed dairy allergies. It is non-irritating, non-sensitizing and has very low comedogenic potential. As with any new skincare ingredient, perform a quick patch test to ensure personal compatibility before full-face use.

Was this article helpful?
More from Glooshi:
ADVERTISEMENT
Get all our top headlines in beauty.
Delivered right to your inbox each week. Zero spam, all goodness, opt-out at anytime.
This site is protected by reCAPTCHA and the Google Privacy Policy and Terms of Service apply.
Get the latest beauty news, top product recommendations & brand-exclusive discount codes direct to your inbox.
Send good feedback:

All feedback is greatly appreciated, anonymous, and will be used to improve the quality of our articles.

This site is protected by reCAPTCHA and the Google Privacy Policy and Terms of Service apply.
Send bad feedback:

All feedback is greatly appreciated, anonymous, and will be used to improve the quality of our articles.

This site is protected by reCAPTCHA and the Google Privacy Policy and Terms of Service apply.
Search